Abstract: By using the design of three factors-five levels-quadratic general spinning ，the effects of applying different amounts of N，P fertilizers an d moisture on the yields of maize and soybean under the eondition of inter-cropping were studied．The results show that the effect of thre factors on soybean yield is moisture> N>P．the effect of three factors on soybean yield is mo isture>P>N．while in the eficiency of mo isture-fertilizer interaction the moisture efficiency iS more than that of fertilizer，and the fertilizer efficiency increases with the increasing of irrigation．