Abstract: The field experiments were carried out by using the principle of agricultural systems engineering and the modular design between quadratic regression and positive rotation，in which the factors of the density(x₁)，amount of fertilizer N applied(x₂)，amount of P₂0₅ applied(x₃)，amount of K₂O applied(x₄)were taken as the adjusting factors，and the yield(y)and benefit(y_b)of per hm²，as the index function．A mathematical model，which show the relationships among the yield，benefit of wheat and the different agronomic measures，is established．After optimizing the combination among different planting measures by computer，the yield of wheat exceeds 7500kg／hm² and the benefit exceeds 6750 Yuan／hm² ．In this article the interactive effects between different agronomic measures are also studied，which provides scientific basis for the high yield and high benefit of the wheat．