Abstract: Soybean yield and growth processes were simulated based on long-term effects of water and fertilizer application at the Hailun Experimental Station of Agricultural Ecology, Chinese Academy of Sciences. A database for the soybean cultivar genetic characters and related model parameters were established for the modeling. The soybean phenology, yield and soil water for different growth stages were validated with DSSAT-CropGro-Soybean model. The analysis indicates that the model simulates phenological stages of soybean with only -2%～3% relative error and a RMSE of 2.3. Crop yield for different years and different field treatments has a relative error range of -7%～9%, 75.9 RMSE and 0.8 EF. The model result for soil water content in different soil layers is good.